Evolution of the extinct Sabretooths and the American cheetah-like cat

The sabretooths (Smilodon and Homotherium) and the American cheetah-like cat (Miracinonyx) were the top predators in Late Pleistocene America, but became extinct about 13 thousand years ago. As the evolutionary history of these taxa remains poorly understood , we analysed their phylogenetic relationship to extant felids. In contrast to previous molecular studies , our results show that the sabretooths diverge early and are not closely related to any living cats. This supports their morphological placement in a separate subfamily (Machairodontinae). Despite its remarkable morphological similarity to the African cheetah (Acinonyx jubatus), Miracinonyx appears to have evolved from a puma-like ancestor, presumably in response to similar ecological pressures.

The reproductive biology of Cybistax antisyphilitica (Bignoniaceae), a characteristic tree of the South American savannah-like "Cerrado" vegetation

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin

A finely tuned Ca2+ signaling system is essential for cells to transduce extracellular stimuli, to regulate growth, and to differentiate. We have recently cloned CaT-like (CaT-L), a highly selective Ca2+ channel closely related to the epithelial calcium channels (ECaC) and the calcium transport protein CaT1. CaT-L is expressed in selected exocrine tissues, and its expression also strikingly correlates with the malignancy of prostate cancer. The expression pattern and selective Ca2+ permeation properties suggest an important function in Ca2+ uptake and a role in tumor progression, but not much is known about the regulation of this subfamily of ion channels. We now demonstrate a biochemical and functional mechanism by which cells can control CaT-L activity. CaT-L is regulated by means of a unique calmodulin binding site, which, at the same time, is a target for protein kinase C-dependent phosphorylation. We show that Ca2+-dependent calmodulin binding to CaT-L, which facilitates channel inactivation, can be counteracted by protein kinase C-mediated phosphorylation of the calmodulin binding site.

The Black cat

Title from cover.

When the cat's away; a comedy in one act for young ladies.

Mode of access: Internet.

Corporeal prisons: dynamics of body and mise-en-scène in three films by Paul Schrader

This thesis focuses on the complex relationship between representations of the human body and the formal processes of mise-en-scène in three consecutive films by the writer-director Paul Schrader: American Gigolo (1980), Cat People (1982) and Mishima: A Life in Four Chapters (1985). While Schrader’s work has typically been critiqued under the broad category of masculinity in crisis (and often as a subset of the films of his more famous long-time collaborator, Martin Scorsese), I focus on a fiveyear early period of his filmography when he sought to explore his key themes of bodily crisis, fragmentation and alienation through an unusually intense focus upon the expressive potential of film form, specifically via the combined elements of colour, lighting, camerawork and production design. By approaching these three films as corporeal character studies of troubled figures whose emotional and psychosexual neurosis is experienced in and through the body, I will locate Schrader’s filmmaking process and style within the thematic and aesthetic contexts of both his own early film criticism and the European and Japanese art cinemas that he claims as his primary influence. In doing so, I will establish Schrader’s position as a director whose literary and theological background differentiated him from his peers of the postclassical Hollywood generation, and who thus continually sought to develop his own visual literacy through his relationship with the camera and his collaborations with more overtly style-oriented film artists. But instead of merely focusing on mise-en-scène to gain a formalist appreciation of these films, I mobilise stylistic analysis as a new critical approach towards the problematic discourses of identity and embodiment that have haunted Schrader’s career from the beginning. In particular, I argue that paying closer attention to Schrader’s formal choices sheds new light on how these films – which he approached as exercises in style – repeatedly deal with the volatile and unavoidably body-oriented categories of race, gender and sexuality. In the process, I argue that a formalist attentiveness to mise-en-scène can also provide valuable cultural insights into Schrader’s oeuvre.

Resiliencia y variables socio demográficas: implicaciones en la dirección de organizaciones

En el ámbito organizacional es necesario interiorizar y aplicar conceptos que generen herramientas que hagan posible el adecuado funcionamiento de las empresas a efectos de mejorar los resultados en términos económicos. Es importante entender las circunstancias que rodean al mundo y así mismo la manera en la que este funciona, ya que cada vez se ve influenciado por culturas y rasgos que difieren según el espacio geográfico en el que se desarrolle la actividad. Por este motivo es importante identificar personas que influencien positivamente a las organizaciones y sean agentes de cambio que desarrollen planes y estrategias que sean comunes a los objetivos de la organización orientando todos sus esfuerzos a la consecución de metas que la misma se proponga. En las empresas es claro que pueden presentarse problemas que encierren cualquier ámbito, como el personal, empresarial o familiar, lo cual a su vez puede generar desmotivación y falta de ánimo entre quienes desarrollen el rol de líder haciendo que sus responsabilidades no se cumplan a cabalidad. Sin embargo, estos deben tener la capacidad de anteponerse ante este tipo de adversidades de manera profesional con el fin de equilibrar sus emociones y superar el obstáculo de manera satisfactoria, sin pensar en resultados negativos y siendo un ejemplo para sus seguidores; dicha capacidad hoy en día se denomina resiliencia. Por esta razón, a lo largo de este trabajo se realizará una revisión teórica que tendrá como objeto identificar los aspectos generales del concepto de resiliencia y de igual forma encontrar la importancia de este estudio dentro del ámbito organizacional. Así mismo, se analizará la relación existente entre la resiliencia y las variables socio-demográficas: edad, nivel de estudios, estrato económico y género. Dicho análisis se hará posible con la ayuda de estudios realizados a nivel latinoamericano en países como: México, Perú y Colombia.

La heterogeneidad de la imagen de China en la política exterior latinoamericana. Perspectivas para la concertación de políticas (Tema Central)

The text shows the heterogeneous views of various Latin American countries, like Mexico, Brazil, Argentina, Chile, Colombia and Venezuela, in terms of their analyses of and studies about foreign policy. This paper aims to make clear the different images that China generates as a rising power in the world economy, particularly as a major trade partner of these countries. The goal of this article is to provide elements for analysis about policy coordination vis-àvis China. The central argument states that there should be coordination between regional integration strategies and foreign policies in relation to China. However, these heterogeneous visions can work against that goal as well.

Has China displaced its competitors in high tech trade?

This paper empirically investigated the extent to which China displaced its competitors in high-tech exports using disaggregated data for the period 1992–2013. To address the endogeneity problem, we used a comprehensive set of instruments for Chinese high-tech exports in relevant markets, including China's GDP and distances to those markets. Results of our IV regressions revealed that in most of the high-tech sectors, Chinese exports had displaced the exports of its developing competitors such as India, South American exporters like Brazil and Mexico, and South-East Asian countries like Malaysia, Singapore, Thailand and Vietnam, especially in the period prior to the 2007–08 global financial crisis. Yet, Chinese exports had been associated with more high-tech exports of developed exporters like OECD countries, South Korea and Japan. Our findings suggest that while China became the world's top high-tech exporter, its high-tech exported products had been substitutes to those of other developing and emerging economies but complementary to that of developed economies.

Studies on the Parasitic Helminths of the North Central States. II. Helminths of Voles (Microtus spp.) Preliminary Report

The helminths of North American mouse-like rodents have received little study. Previous work has been based on low numbers of animals examined, and there has been little reference to the ecology involved. The purpose of this paper is to present data resulting from the examination of over 600 voles, with special reference to host-parasite relationships

Getting ahead collectively : grassroots experiences in Latin America /

[cat;jmn]

Perspectivas de los biocombustibles en Colombia

Colombia se está iniciando en bioenergía y necesita de políticas e infraestructura para la producción de biocombustibles. En los últimos años, losbiocombustibles vienen avanzando apoyados por la adopción de decretos de ley que permiten la introducción de biocombustibles, mezclados, en primera instancia, con combustibles fósiles como la gasolina y el diésel. Este artículo de “revisión de tema” presenta el comienzo y desarrollo de los biocombustibles en Colombia y la situación actual de la producción, las empresas y las entidades que lideran este proyecto, con el fin de adoptar una fuente de energía renovable y sostenible. En el análisis de este tema sobre biocombustibles en Colombia se apunta un claro comienzo a la independencia de combustibles fósiles, con la premisa de una matriz energética sostenible que asegure el crecimiento de la industria, el desarrollo social y la preservación del ambiente. Por otro lado, se observa la tendencia mundial a la adopción de biocombustibles principalmente en países dependientes del petróleo, siendo los suramericanos como Brasil, Colombia y Argentina los abanderados en estas propuestas. Colombia presenta, a su vez, recursos en este ámbito en disponibilidad de tierras, mano de obra, políticas internas de consumo y producción, que coexisten con dificultades en desigualdad social, conflictos internos, monopolios y trabas políticas que podrían impedir inversión privada y extranjera

Nitrate in groundwater in a recharge area of Guarany aquifer in Brazil.

The region of Ribeirão Preto City located in São Paulo State, southeastern Brazil, is an important sugarcane, soybean and corn producing area. This region is also an important recharge area (Espraiado) for groundwater of the Guarany aquifer, a water supply source for the city and region. It has an intercontinental extension that comprises areas of eight Brazilian states, as well as significant portions of other South American countries like Argentina, Uruguay, and Paraguay, with a total area of approximately 1,200,000 Km2. Due to the high permeability of some soils present in this region, the high mobility of the herbicides and fertilizers applied, and being a recharge area, it is important to investigate the potential transport of applied fertilizers to underlying aquifer. The cultivation sugar cane in this area demands the frequent use of nitrogen as fertilizer. This research was conducted to characterize the potential contamination of groundwater with nitrogen in the recharge area of groundwater. Seven groundwater sample points were selected in the Espraiado stream watershed, during the years of 2005 and 2006. Samples were collected during the months of March, July, and December of each year. Three replications were collected at each site. Groundwater was also collected during the same months from county groundwater wells located throughout the city. The following six wells were studied: Central, Palmares, Portinari, Recreio Internacional, São Sebastião, and São José. Nitrate water samples were analyzed by Cadmium Reduction Method. No significant amount of nitrate was found in the recharge, agricultural, area. However, nitrate levels were detected at concentrations higher than the Maximum Concentration Level (MCL) of 10mg/L in downtown, urban, well located away from agricultural sites with no history of fertilizer or nitrogen application.

Prosthetic valve endocarditis caused by a Pasteurella dagmatis-like isolate originating from a patient's cat

Pasteurella species are part of the oral flora of cats and dogs. In humans, they are frequently found in infected animal bite wounds, but invasive infections are rare. This is the first report of prosthetic-valve endocarditis with a Pasteurella dagmatis-like species, which originated from the patient's cat.

Phylogenetic analysis of Trypanosoma vivax supports the separation of South American/West African from East African isolates and a new T-vivax-like genotype infecting a nyala antelope from Mozambique

In this study, we addressed the phylogenetic and taxonomic relationships of Trypanosoma vivax and related trypanosomes nested in the subgenus Duttonella through combined morphological and phylogeographical analyses. We previously demonstrated that the clade T. vivax harbours a homogeneous clade comprising West African/South American isolates and the heterogeneous East African isolates. Herein we characterized a trypanosome isolated from a nyala antelope (Tragelaphus angasi) wild-caught in Mozambique (East Africa) and diagnosed as T. vivax-like based on biological, morphological and molecular data. Phylogenetic relationships, phylogeographical patterns and estimates of genetic divergence were based on SSU and ITS rDNA sequences of T. vivax from Brazil and Venezuela (South America), Nigeria (West Africa), and from T. vivax-like trypanosomes from Mozambique, Kenya and Tanzania (East Africa). Despite being well-supported within the T. vivax clade, the nyala trypanosome was highly divergent from all other T. vivax and T. vivax-like trypanosomes, even those from East Africa. Considering its host origin, morphological features, behaviour in experimentally infected goats, phylogenetic placement, and genetic divergence this isolate represents a new genotype of trypanosome closely phylogenetically related to T. vivax. This study corroborated the high complexity and the existence of distinct genotypes yet undescribed within the subgenus Duttonella.